
| Source: | Rabbit | Gene Id: | 4077 |
| Isotype: | IgG | Swiss Prot: | Q14596 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 107kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
|
| Immunogen | A recombinant protein of human NBR1 |
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | IAI3B, M17S2, MIG19, 1A1-3B |
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