| No | Size | Price | Availability | |
| ARP1981-02 | 50ul | 1500.00 | In Stock |  |
| ARP1981-02 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1981 |
| Isotype: | IgG | Swiss Prot: | Q04637 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 175kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
|
| Immunogen | A synthetic peptide of human EIF4G1 |
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | P220, EIF4F, EIF4G, EIF4GI, PARK18, EIF-4G1 |
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