Source: | Rabbit | Gene Id: | 7293 |
Isotype: | IgG | Swiss Prot: | P43489 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 29kDa |
Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
|
Immunogen | A recombinant protein of human TNFRSF4 |
Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | OX40, ACT35, CD134, IMD16, TXGP1L |
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