Source: | Rabbit | Gene Id: | 2547 |
Isotype: | IgG | Swiss Prot: | P12956 |
purity: | Affinity purification |
Background: |
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 70kDa |
Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
|
Immunogen | A recombinant protein of human XRCC6 |
Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | ML8, KU70, TLAA, CTC75, CTCBF, G22P1 |
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