| No | Size | Price | Availability | |
| ARP7942-02 | 50ul | 1500.00 | In Stock |  |
| ARP7942-02 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7942 |
| Isotype: | IgG | Swiss Prot: | P19484 |
| purity: | Affinity purification |
| Background: |
| Transcription factor EB(TFEB) is one of the transcription factors that contain a basic HLH-ZIP domain(for DNA binding ) and HLH and ZIP domains( for loigomerization). TFEB specifically recognizes and binds to E-box sequences, which required dimerization with itself or another MiT/TFE family member. It plays a role in T-cell-dependent antibody responses to activated CD4+ T-cells and thymus-dependent humoral immunity once associated with TFE3. It also activates lysosomal gene by binding the CLEAR-box sequence in the regulatory region. It involves in the signal transduction processes required for normal vascularization of the placenta. This is a rabbit polyclonal antibody raised against the full length of human TFEB. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 53 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
IF 1:50-1:100
|
| Immunogen | A recombinant protein of human TFEB |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | AlphaTFEB, bHLHe35, TCFEB, TFEB, transcription factor EB |
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