IKZF3 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP22806-01 50ul 1500.00 In Stock
ARP22806-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 22806
Isotype: IgG Swiss Prot: Q9UKT9
purity: Affinity purification
Background:
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
Reactivity Human
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW 58kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:100
Immunogen A recombinant protein of human IKZF3
Storage Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym AIO, AIOLOS, ZNFN1A3
This product is for research use only, not for diagnostic or therapeutic use!

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