IDH2 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP3418-01 50ul 1500.00 In Stock
ARP3418-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 3418
Isotype: IgG Swiss Prot: P48735
purity: Affinity purification
Background:
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF IP
Clonality Polyclonal Antibody
Calculated MW 51kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:50
Immunogen A recombinant protein of human IDH2
Storage Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym IDH, IDP, IDHM, IDPM, ICD-M, D2HGA2, mNADP-IDH
This product is for research use only, not for diagnostic or therapeutic use!

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