Source: | Rabbit | Gene Id: | 5978 |
Isotype: | IgG | Swiss Prot: | Q13127 |
purity: | Affinity purification |
Background: |
This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described |
Reactivity | Human |
Tested applications | WB IF |
Clonality | Polyclonal Antibody |
Calculated MW | 122kDa |
Recommended Dilutions |
WB 1:500 - 1:2000
IF 1:50 - 1:200
|
Immunogen | A recombinant protein of human REST |
Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | XBR, NRSF |
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