| No | Size | Price | Availability | |
| ARP84433-01 | 50ul | 1500.00 | In Stock |  |
| ARP84433-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 84433 |
| Isotype: | IgG | Swiss Prot: | Q9BXL7 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 133kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:100
|
| Immunogen | A recombinant protein of human CARD11 |
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | PPBL, BENTA, BIMP3, IMD11, CARMA1 |
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