| No | Size | Price | Availability | |
| ARP51433-01 | 50ul | 1500.00 | In Stock |  |
| ARP51433-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 51433 |
| Isotype: | IgG | Swiss Prot: | Q9UJX4 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 85kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
|
| Immunogen | A recombinant protein of human ANAPC5 |
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | APC5 |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
