DAP3 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP7818-01 50ul 1500.00 In Stock
ARP7818-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 7818
Isotype: IgG Swiss Prot: P51398
purity: Affinity purification
Background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 46kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunogen A recombinant protein of human DAP3
Storage Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym DAP-3, MRPS29, MRP-S29, bMRP-10
This product is for research use only, not for diagnostic or therapeutic use!

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