| No | Size | Price | Availability | |
| ARP5890-01 | 50ul | 1500.00 | In Stock |  |
| ARP5890-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5890 |
| Isotype: | IgG | Swiss Prot: | O15315 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. |
| Reactivity | Human |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 42kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:100
|
| Immunogen | A recombinant protein of human RAD51L1 |
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | REC2, R51H2, RAD51L1 |
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