| No | Size | Price | Availability | |
| ARP5565-02 | 50ul | 1500.00 | In Stock |  |
| ARP5565-02 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5565 |
| Isotype: | IgG | Swiss Prot: | O43741 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 30kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:100
|
| Immunogen | A recombinant protein of human PRKAB2 |
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
