PLOD2 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5352-01 50ul 1500.00 In Stock
ARP5352-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5352
Isotype: IgG Swiss Prot: O00469
purity: Affinity purification
Background:
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Reactivity Human
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW 85kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:100
Immunogen A recombinant protein of human PLOD2
Storage Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym LH2, TLH
This product is for research use only, not for diagnostic or therapeutic use!

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