| No | Size | Price | Availability | |
| ARP5158-01 | 50ul | 1500.00 | In Stock |  |
| ARP5158-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5158 |
| Isotype: | IgG | Swiss Prot: | P35913 |
| purity: | Affinity purification |
| Background: |
| Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 98kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
|
| Immunogen | A recombinant protein of human PDE6B |
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | rd1, PDEB, RP40, CSNB3, CSNBAD2 |
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