Source: | Rabbit | Gene Id: | 68585 |
Isotype: | IgG | Swiss Prot: | Q99P72 |
purity: | Purified by Protein A. |
Background: |
Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex. May inhibit BACE1 activity and amyloid precursor protein processing. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from mouse RTN4 protein |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | ASY, NgA, NOGO, NSP-CL, Nogo-A, Nogo-B, Nogo-C, AA407876, AA409940, AA960376, mKIAA0886, mKIAA4153, 1110020G17Rik, C130026I10Rik, Reticulon-4, Neurite outgrowth inhibitor, Nogo protein, Rtn4, Kiaa0886 |
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