Source: | Rabbit | Gene Id: | 6419 |
Isotype: | IgG | Swiss Prot: | Q53H47 |
purity: | Affinity purification |
Background: |
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. |
Reactivity | Human |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | 76kDa |
Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50- 1:100
|
Immunogen | A recombinant protein of human SETMAR |
Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | Mar1, HsMar1, METNASE |
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