| No | Size | Price | Availability | |
| YRP11170-01 | 50ul | 1500.00 | In Stock |  |
| YRP11170-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Sidekick-2 (SDK2), also known as KIAA1514, is a 2,172 amino acid single-pass type I membrane protein containing thirteen fibronectin type-III domains and six Ig-like C2-type (immunoglobulin-like) domains. Acting as a cell adhesion protein, Sidekick-2 guides axonal terminals to synapses in developing neurons. Sidekick-2 may require the interaction with MAGI scaffolding proteins for proper localization and function. Existing as four alternatively spliced isoforms, the gene encoding Sidekick-2 maps to human chromosome 17q25.1. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth have been linked to chromosome 17. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | FC IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
FC 1:20-1:100
|
| Immunogen | KLH conjugated synthetic peptide derived from human Sidekick 2 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | SDK2, SDK 2, SDK-2, SDK2, Sidekick 2, Sidekick homolog 2 chicken, sidekick-2, Sidekick2, FLJ10832, KIAA1514, SDK2_HUMAN. |
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