
| Source: | Rabbit | Gene Id: | 23532 |
| Isotype: | IgG | Swiss Prot: | P78395 |
| purity: | Affinity purification |
| Background: |
| This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. |
| Reactivity | Human |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 57kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50- 1:100
|
| Immunogen | A recombinant protein of human PRAME |
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | MAPE, OIP4, CT130, OIP-4 |
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