
| Source: | Rabbit | Gene Id: | 10267 | 
| Isotype: | IgG | Swiss Prot: | O60894 | 
| purity: | Affinity purification | 
| Background: | 
| The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. | 
| Reactivity | Human | 
| Tested applications | WB IHC | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 16kDa | 
| Recommended Dilutions | 
                                     WB 1:500 - 1:2000 
                                    IHC 1:50 - 1:200 
                                    
                                    
                                    
                                    
                                    
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| Immunogen | A recombinant protein of human RAMP1 | 
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | 
| Synonym | 
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