
| Source: | Rabbit | Gene Id: | 9377 | 
| Isotype: | IgG | Swiss Prot: | P20674 | 
| purity: | Affinity purification | 
| Background: | 
| Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. | 
| Reactivity | Human | 
| Tested applications | WB IHC | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 16kDa | 
| Recommended Dilutions | 
                                     WB 1:500 - 1:2000 
                                    IHC 1:50 - 1:200 
                                    
                                    
                                    
                                    
                                    
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| Immunogen | A recombinant protein of human COX5A | 
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | 
| Synonym | VA, COX, COX-VA | 
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