RAD51 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5888-01 50ul 1500.00 In Stock
ARP5888-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5888
Isotype: IgG Swiss Prot: Q06609
purity: Affinity purification
Background:
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Reactivity Human, Mouse, Rat
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 37 kDa
Recommended Dilutions
WB 1:500-1:1000
Immunogen A recombinant protein of human RAD51
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym RECA, BRCC5, MRMV2, HRAD51, RAD51A, HsRad51, HsT16930
This product is for research use only, not for diagnostic or therapeutic use!

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