COMT Rabbit Polyclonal Antibody
No Size Price Availability  
ARP1312-01 50ul 1500.00 In Stock
ARP1312-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 1312
Isotype: IgG Swiss Prot: P21964
purity: Affinity purification
Background:
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 30kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunogen A recombinant protein of human COMT
Storage Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym HEL-S-98n
This product is for research use only, not for diagnostic or therapeutic use!

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