Source: | Rabbit | Gene Id: | 8520 |
Isotype: | IgG | Swiss Prot: | O14929 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF IP CHIP |
Clonality | Polyclonal Antibody |
Calculated MW | 49kDa |
Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
ChIP 1:20 - 1:100
|
Immunogen | A recombinant protein of human HAT1 |
Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | KAT1 |
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