| No | Size | Price | Availability | |
| ARP8411-01 | 50ul | 1500.00 | In Stock |  |
| ARP8411-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 8411 |
| Isotype: | IgG | Swiss Prot: | Q15075 |
| purity: | Affinity purification |
| Background: |
| EEA1 is an early endosomal marker and a Rab5 effector protein essential for early endosomal membrane fusion and trafficking. The carboxy terminus of EEA1 contains a FYVE domain which binds to phosphatidylinositol-3-phosphate (PtdIns(3)P), targeting EEA1 to early endosomes. The stable association of EEA1 with the endosomal membrane is regulated by PI3 kinase, Rab5 and calcium/calmodulin. Once on the membrane, EEA1 interacts with Rab5, NSF and syntaxin 13 to promote early endosomal membrane docking and fusion. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IP ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 162 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
ICC 1:50-1:200
|
| Immunogen | A synthetic peptide of human EEA1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | MST105, ZFYVE2, MSTP105 |
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