| No | Size | Price | Availability | |
| ARP140690-01 | 50ul | 1500.00 | In Stock |  |
| ARP140690-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 140690 |
| Isotype: | IgG | Swiss Prot: | Q8NI51 |
| purity: | Affinity purification |
| Background: |
| CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 75 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:20-1:100
|
| Immunogen | A recombinant protein of human CTCFL |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CT27, BORIS, CTCF-T, HMGB1L1, dJ579F20.2 |
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