Source: | Rabbit | Gene Id: | 7706 |
Isotype: | IgG | Swiss Prot: | Q14258 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. |
Reactivity | Human, Mouse |
Tested applications | WB IF |
Clonality | Polyclonal Antibody |
Calculated MW | 71 kDa |
Recommended Dilutions |
WB 1:200-1:2000
IF 1:50-1:200
|
Immunogen | A recombinant protein of human TRIM25 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | EFP, Z147, RNF147, ZNF147 |
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