ATM Rabbit Polyclonal Antibody
No Size Price Availability  
ARP472-01 50ul 1500.00 In Stock
ARP472-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 472
Isotype: IgG Swiss Prot: Q13315
purity: Affinity purification
Background:
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
Reactivity Human, Mouse
Tested applications WB IF
Clonality Polyclonal Antibody
Calculated MW 351 kDa
Recommended Dilutions
WB 1:500-1:1000
IF 1:100-1:200
Immunogen A synthetic peptide of human ATM
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1
This product is for research use only, not for diagnostic or therapeutic use!

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