| No | Size | Price | Availability | |
| ARP7520-01 | 50ul | 1500.00 | In Stock |  |
| ARP7520-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7520 |
| Isotype: | IgG | Swiss Prot: | P13010 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
| Reactivity | Human |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 82 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:20-1:100
|
| Immunogen | A recombinant protein of human XRCC5 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | KU80, KUB2, Ku86, NFIV, KARP1, KARP-1 |
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