PRKCB Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5579-01 50ul 1500.00 In Stock
ARP5579-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5579
Isotype: IgG Swiss Prot: P05771
purity: Affinity purification
Background:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 76kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunogen A recombinant protein of human PRKCB
Storage Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym PKCB, PRKCB1, PRKCB2, PKC-beta
This product is for research use only, not for diagnostic or therapeutic use!

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