| No | Size | Price | Availability | |
| ARP5588-11 | 50ul | 1500.00 | In Stock |  |
| ARP5588-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5588 |
| Isotype: | / | Swiss Prot: | Q04759 |
| purity: | Affinity purification |
| Background: |
| Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. |
| Reactivity | Human |
| Tested applications | WB IHC ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | 81.90 kDa |
| Recommended Dilutions |
WB 1:100-1:500
IHC 1:50-1:100
|
| Immunogen | A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PRKCQ |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS with 0.09% sodium azide. Avoid freeze/thaw cycles. |
| Synonym | MGC12651, MGC141919, PRKCT, nPKC-theta |
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