Source: | Rabbit | Gene Id: | 11143 |
Isotype: | IgG | Swiss Prot: | O95251 |
purity: | Affinity purification |
Background: |
MYST2, also named as HBO1, HBOa MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, belongs to the MYST (SAS/MOZ) family. It specifically represses AR mediated transcription. MYST2 is a candidate oncogene. It enhances the anchorage-independent growth of breast cancer cells.(PMID:19372580) MYST2 is a histone acetyltransferase (HAT) which could exert oncogenic function in breast cancer. It is an important downstream molecule of ERa, and ERK1/2 signaling pathway may involved in the expression of HBO1 increased by E2. |
Reactivity | Human, Mouse, Rat, |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 71kDa |
Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
|
Immunogen | A recombinant protein of human KAT7 |
Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | HBO1, HBOA, MYST2, ZC2HC7 |
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