TP53 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP7157-03 50ul 1500.00 In Stock
ARP7157-03 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 7157
Isotype: IgG Swiss Prot: P04637
purity: Affinity purification
Background:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).
Reactivity Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 44kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunogen A recombinant protein of human TP53
Storage Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym P53, BCC7, LFS1, TRP53
This product is for research use only, not for diagnostic or therapeutic use!

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