Source: | Rabbit | Gene Id: | 90427 |
Isotype: | / | Swiss Prot: | Q96LC9 |
purity: | Protein G purification |
Background: |
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Reactivity | Human |
Tested applications | WB IHC ELISA |
Clonality | Polyclonal Antibody |
Calculated MW | 21 kDa |
Recommended Dilutions |
WB 1:50-1:200
IHC 1:50-1:100
|
Immunogen | A synthetic peptide (conjugated with KLH) corresponding to amino acids 130-150 of human BMF |
Storage | Store at 4°C. For long term storage store at -20°C in PBS with 0.09% sodium azide. Avoid freeze/thaw cycles. |
Synonym | FLJ00065 |
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