| No | Size | Price | Availability | |
| ARP4860-01 | 50ul | 1500.00 | In Stock |  |
| ARP4860-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4860 |
| Isotype: | IgG | Swiss Prot: | P00491 |
| purity: | Affinity purification |
| Background: |
| This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 32kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
|
| Immunogen | A recombinant protein of human PNP |
| Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | NP, PUNP, PRO1837 |
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