Source: | Rabbit | Gene Id: | 27429 |
Isotype: | IgG | Swiss Prot: | O43464 |
purity: | Affinity purification |
Background: |
This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | 48 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:50-1:200
|
Immunogen | A recombinant protein of human HTRA2 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | OMI, PARK13, PRSS25 |
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