| Source: | Rabbit | Gene Id: | 581 |
| Isotype: | IgG | Swiss Prot: | Q07812 |
| purity: | Purified by Protein A. |
| Background: |
| Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. |
| Reactivity | Human, Mouse, Rat, Pig, Rabbit |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human Bax |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX |
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