Source: | Rabbit | Gene Id: | 8554 |
Isotype: | / | Swiss Prot: | O75925 |
purity: | Protein G purification |
Background: |
This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. |
Reactivity | Human |
Tested applications | WB IHC ELISA |
Clonality | Polyclonal Antibody |
Calculated MW | 76 kDa |
Recommended Dilutions |
WB 1:100-1:500
IHC 1:50-1:100
|
Immunogen | A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PIAS1 |
Storage | Store at 4°C. For long term storage store at -20°C in PBS with 0.09% sodium azide. Avoid freeze/thaw cycles. |
Synonym | DDXBP1, GBP, GU/RH-II, MGC141878, MGC141879, ZMIZ3 |
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