| No | Size | Price | Availability | |
| ARP8835-11 | 50ul | 1500.00 | In Stock |  |
| ARP8835-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 8835 |
| Isotype: | / | Swiss Prot: | O14508 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control. |
| Reactivity | Human, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 22 kDa |
| Recommended Dilutions |
WB 1 ug/Ml
|
| Immunogen | A synthetic peptide corresponding to C-terminus of human SOCS2 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2 |
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