Source: | Rabbit | Gene Id: | 9252 |
Isotype: | / | Swiss Prot: | O75582 |
purity: | Affinity purification |
Background: |
MSK1, a mitogen and stress activated protein kinase, is activated by Erk as well as p38 MAPK in response to growth factors and cellular stress, respectively. MSK1 resembles RSK because it has two kinase domains connected by a regulatory linker region. Phosphorylation of RSK1 at Ser364 and Ser381 is critical for RSK1 activity. These sites are analogous to Ser360 and Ser376 of MSK1, which may be important for MSK1 activity as well. |
Reactivity | Human, Mouse |
Tested applications | WB IHC ELISA |
Clonality | Polyclonal Antibody |
Calculated MW | 90 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:100
|
Immunogen | A synthetic peptide corresponding to residues surrounding S360 of human RPS6KA5 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | MGC1911, MSK1, MSPK1, RLPK |
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