Source: | Rabbit | Gene Id: | 3674 |
Isotype: | IgG | Swiss Prot: | P08514 |
purity: | Affinity purification |
Background: |
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 113 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A recombinant protein of human ITGA2B |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | GT, GTA, CD41, GP2B, HPA3, CD41B, GPIIb, BDPLT2, BDPLT16 |
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