CCNA1 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP8900-01 50ul 1500.00 In Stock
ARP8900-01 100ul 2000.00 In Stock
  • Details
  • FAQs
  • Manual
Source: Rabbit Gene Id: 8900
Isotype: IgG Swiss Prot: P78396
purity: Affinity purification
Background:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Reactivity Human
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 52kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunogen A recombinant protein of human CCNA1
Storage Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym
This product is for research use only, not for diagnostic or therapeutic use!

backtop
QQ
service center
Contact Us