Source: | Rabbit | Gene Id: | 5743 |
Isotype: | IgG | Swiss Prot: | P35354 |
purity: | Affinity purification |
Background: |
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. |
Reactivity | Human |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 74 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A recombinant protein of human COX2 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | PTGS2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2, GRIPGHS |
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