APLP2 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP334-01 50ul 1500.00 In Stock
ARP334-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 334
Isotype: IgG Swiss Prot: Q06481
purity: Affinity purification
Background:
This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Reactivity Human, Mouse, Rat,
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW 87kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50- 1:200
Immunogen A recombinant protein of human APLP2
Storage Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym APPH, APPL2, CDEBP, APLP-2
This product is for research use only, not for diagnostic or therapeutic use!

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