Source: | Rabbit | Gene Id: | 11035 |
Isotype: | IgG | Swiss Prot: | E9PZP3 |
purity: | Affinity purification |
Background: |
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. |
Reactivity | Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 56 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A recombinant protein of Mouse RIPK3 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | RIP3 |
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