Source: | Rabbit | Gene Id: | 23410 |
Isotype: | IgG | Swiss Prot: | Q9NTG7 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 43 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A recombinant protein of human SIRT3 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | SIR2L3 |
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