HUS1 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP3364-01 50ul 1500.00 In Stock
ARP3364-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 3364
Isotype: IgG Swiss Prot: O60921
purity: Affinity purification
Background:
The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW 31kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Immunogen A recombinant protein of human HUS1
Storage Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym hHUS1
This product is for research use only, not for diagnostic or therapeutic use!

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