| No | Size | Price | Availability | |
| ARP86-01 | 50ul | 1500.00 | In Stock |  |
| ARP86-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 86 |
| Isotype: | IgG | Swiss Prot: | O96019 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. |
| Reactivity | Human, Mouse, Rat, |
| Tested applications | WB IHC IF IP CHIP |
| Clonality | Polyclonal Antibody |
| Calculated MW | 47kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
ChIP 1:20 - 1:100
|
| Immunogen | A recombinant protein of human ACTL6A |
| Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | Arp4, ACTL6, BAF53A, INO80K, ARPN-BETA |
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