
| Source: | Rabbit | Gene Id: | 56852 |
| Isotype: | IgG | Swiss Prot: | Q9NS91 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 56 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:20
IF 1:50-1:200
|
| Immunogen | A recombinant protein of human RAD18 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | RNF73 |
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