DBI Rabbit Polyclonal Antibody
No Size Price Availability  
ARP1622-01 50ul 1500.00 In Stock
ARP1622-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 1622
Isotype: IgG Swiss Prot: P07108
purity: Affinity purification
Background:
This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
Reactivity Human, Mouse, Rat,
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW 10kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50- 1:200
Immunogen A recombinant protein of human DBI
Storage Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym EP, ACBP, ACBD1, CCK-RP
This product is for research use only, not for diagnostic or therapeutic use!

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